Difference between revisions of "INF-BIOX121 H15 curriculum"

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[https://wiki.uio.no/projects/clsi/images/7/75/Sims2014.pdf Sims ''et al.'', Sequencing depth and coverage: key considerations in genomic analyses. ''Nature Reviews Genetics'' 2011]
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[https://wiki.uio.no/projects/clsi/images/1/1d/Depristo2011.pdf DePristo ''et al.'' A framework for variation discovery and genotyping using next-generation DNA sequencing data. ''Nature Genetics'' 2011]

Revision as of 14:56, 9 September 2015

Curriculum for INF-BIO5/9121

Work in progress!! Everything that is already here will be in the curriculum, but we are currently adding papers to the list.

The fields of bioinformatics and genomics are in rapid development. Hence, the curriculum for this course is not a book, but a set of articles. We have put together two sets of articles for this course. The first comprises the core curriculum, these are articles from which questions for the exam might be pulled. The second set is a list of articles that will give more in-depth information. These articles will not be used for the exam, but still represent highly useful and relevant knowledge that we highly recommend reading.

Core curriculum

Sequencing

Buermans et al., Next generation sequencing technology: Advances and applications Biochimica et Biophysica Acta 2014

Assembly

Miller et al., Assembly algorithms for next-generation sequencing data Genomics. 2010

Amemiyaet al., The African coelacanth genome provides insights into tetrapod evolution Nature 2014

Brawand et al., The genomic substrate for adaptive radiation in African cichlid fish Nature 2014


RNASeq

Martin et al., Next-generation transcriptome assembly Nature 2011

Verbruggen et al., De novo assembly of the Carcinus maenas transcriptome and characterization of innate immune system pathways Genomics 2015

Variant Calling

Nielsen et al., Genotype and SNP calling from next-generation sequencing data. Nature Reviews Genetics 2011

Ng et al., Exome sequencing identifies the cause of a mendelian disorder. Nature Genetics 2010

Barøy et al., A novel type of rhizomelic chondrodysplasia punctata, RCDP5, is caused by loss of the PEX5 long isoform. Human Molecular Genetics 2015


Recommended reading

Sequencing

Metzker Sequencing technologies — the next generation Nature Reviews Genetics 2010

Ross et al., Characterizing and measuring bias insequence data Genome Biology 2013

NGS Field Guide

Assembly

Baker, De novo genome assembly: what every biologist should know Nature Methods 2012

Star et al., The genome sequence of Atlantic cod reveals a unique immune system Nature 2011

Ekblom et al., A field guide to whole-genome sequencing, assembly and annotation Evolutionary Applications 2014

RNASeq

Hackett et al., Transcriptional maturation of the mouse auditory forebrain. BMC Genomics 2015

Brwon et al., RNA Sequencing with Next-Generation Sequencing. Next-Generation DNA Sequencing Informatics, 2nd edition.

Variant Calling

Sims et al., Sequencing depth and coverage: key considerations in genomic analyses. Nature Reviews Genetics 2011

DePristo et al. A framework for variation discovery and genotyping using next-generation DNA sequencing data. Nature Genetics 2011