Difference between revisions of "TTA / TetOff Atlas III (Nop)"

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Revision as of 13:38, 22 October 2015

About The tTA atlas III (Nop) is an interactive resource providing access to brain-wide histological images documenting the activity of the Nop-tTA promoter in bigenic mice in which the Nop-tTA promoter regulates the expression of the LacZ reporter gene, encoding the histologically detectible marker β-galactosidase. Detailed knowledge about where in the brain gene expression is regulated is essential for the use and interpretation of such models.

Access image repository The virtual microscopy viewer allows interactive zooming and panning. Original images are available for download via separate link. Re-use of data from this repository is allowed provided that reference is given to the following publication: Yetman MJ, Lillehaug S, Bjaalie JG, Leergaard TB, Jankowsky JL. Transgene expression in the Nop-TTA driver line is not inherently restricted to the entorhinal cortex. Brain Struct Funct. 2015. DOI 10.1007/s00429-015-1040-9